Melkersson Rosenthal syndrome in a patient with granulomatous cheilitis about a case reported in the General Teaching Hospital of Riobamba as a single clinical manifestation

Authors

  • Carlos Martínez Fiallos Hospital Provincial General Docente de Riobamba. Riobamba, Ecuador.
  • Miriam Arboleda Hospital General Docente de Ambato. Ambato, Ecuador.
  • María Gabriela Martinez Universidad Técnica de Ambato. Ambato, Ecuador.

DOI:

https://doi.org/10.63787/5/1/2023/74-87

Keywords:

granulomatous cheilitis, Melkersson Rosenthal syndrome, labial edema, facial paralysis, fissured tongue

Abstract

Miescher’s granulomatous cheilitis is characterized by the appearance of recurrent labial edema on one or both lips, which may be persistent. It has been considered as a monosymptomatic form of Melkersson Rosenthal syndrome. This syndrome usually occurs with edema either in the upper or lower lip, facial paralysis and fissured tongue. It is an infrequent one, with few cases described, although it may be underdiagnosed due to its lack of knowledge. The diagnosis of granulomatous cheilitis is mostly clinical, although its diagnosis can also be confirmed by histological evaluation. After carrying out its diagnosis, a comprehensive evaluation of the patient should be recommended, in order to rule out the rest of the syndromic associations described in the medical literature.

The clinical case presented is a 20-year-old man with a clinical picture of lower lip edema, asthenia, dizziness and fissured tongue, who had a good clinical evolution and recovery.

We opted for the presentation of the clinical case of Melkersson Rosenthal Syndrome in a patient with granulomatous cheilitis as it is a rare entity with unique clinical characteristics for its diagnosis.

Published

2026-07-17

How to Cite

Martínez Fiallos, C., Arboleda, M., & Martinez, M. G. (2026). Melkersson Rosenthal syndrome in a patient with granulomatous cheilitis about a case reported in the General Teaching Hospital of Riobamba as a single clinical manifestation. Revista Dermatologica Centro Úraga, 5(1), 74–87. https://doi.org/10.63787/5/1/2023/74-87